Relict plant species have evolved biochemical strategies to withstand environmental stress, including the accumulation of antioxidant compounds. This study evaluated the antioxidant and antiviral properties of leaf extracts from Buxus sempervirens, Ruscus hyrcanus, and Parrotia persica. Antioxidant activity was assessed using the DPPH radical scavenging method, with B. sempervirens showing the strongest effect at 0,04 µg/ml. Resistance of photosynthetic pigments (chlorophyll a and b) to photobleaching under high-intensity light exposure was also analyzed, revealing greater pigment stability in B. sempervirens compared to the other species. To assess antiviral activity, cherry rootstocks (Gizella 6) infected with PNRSV were treated with the extracts. By the sixth week, treated plants exhibited reduced symptom severity and increased healthy leaf count, particularly with B. sempervirens and R. hyrcanus extracts. These findings suggest that specific relict species possess antioxidant and antiviral properties that may contribute to stress tolerance through the protection of photosynthetic function and membrane integrity.